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Transcription Factor AP-1 Drives Oncogene Expression in Lung Cancer via Promoter–Enhancer Rewiring

A study published in Cancer Gene Therapy demonstrates that the transcription factor AP-1 plays a central role in promoting oncogenic transcription in non-small cell...

Profluent and Ensoma Initiate Collaboration on AI-Designed Base Editors for In Vivo Hematopoietic Stem Cell Therapies

Profluent, a biotechnology company focused on computational protein engineering, and Ensoma, an in vivo cellular engineering firm developing one-time genomic therapies, have announced a...

BenchSci and Merck Extend Collaboration to Advance AI-Enabled Biological Discovery

BenchSci has renewed a two-year agreement with Merck (known as MSD outside the United States and Canada), extending the deployment of its neurosymbolic artificial...

Real-World Evidence From Commercial Use of Lentiviral Gene Therapies in Hemoglobinopathies Shows Increasing Uptake and Ongoing Safety Considerations

Genetix Biotherapeutics reported updated real-world data at the 2025 American Society of Hematology (ASH) Annual Meeting describing early outcomes and implementation metrics from commercial...

Neonatal DNA Methylation Signatures Associated With Subsequent Risk of Childhood Acute Lymphoblastic Leukemia

Investigators from Children’s Hospital Los Angeles (CHLA) have reported evidence that epigenetic differences measurable at birth are associated with later development of childhood acute...

Natera Acquires Foresight Diagnostics

Natera, has announced the completion of its acquisition of Foresight Diagnostics, a molecular oncology diagnostics company specializing in ultrasensitive detection of circulating tumor DNA...

The interplay between diet and the human gut microbiome is exceedingly complex

A study published in Nature, Faecal metabolites as a readout of habitual diet capture dietary interactions with the gut microbiome offers compelling evidence that...

Foundation Medicine reaches 100 approved companion diagnostic indications in the United States and Japan

Foundation Medicine has reached a regulatory milestone, reporting 100 approved companion diagnostic indications across the United States and Japan for its next-generation sequencing platforms...

LabGenius Therapeutics Announces New Collaboration with Sanofi

LabGenius Therapeutics has announced the initiation of a second research collaboration with Sanofi aimed at advancing the design and optimisation of therapeutic NANOBODY® molecules...

Large WGS study maps genomic drivers and biomarkers in breast cancer

Researchers have published the largest clinically annotated, whole-genome sequencing (WGS) study of breast cancer to date, analysing 1,364 tumors to uncover new driver genes,...