A new study published by Ambry Genetics, examining exome sequencing outcomes across racial, ethnic, and ancestral (REA) groups reveals that disparities persist not only in the initial diagnostic yield...

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Transcription Factor AP-1 Drives Oncogene Expression in Lung Cancer via Promoter–Enhancer Rewiring

A study published in Cancer Gene Therapy demonstrates that the transcription factor AP-1 plays a central role in promoting oncogenic transcription in non-small cell...

Profluent and Ensoma Initiate Collaboration on AI-Designed Base Editors for In Vivo Hematopoietic Stem Cell Therapies

Profluent, a biotechnology company focused on computational protein engineering, and Ensoma, an in vivo cellular engineering firm developing one-time genomic therapies, have announced a...

Real-World Evidence From Commercial Use of Lentiviral Gene Therapies in Hemoglobinopathies Shows Increasing Uptake and Ongoing Safety Considerations

Genetix Biotherapeutics reported updated real-world data at the 2025 American Society of Hematology (ASH) Annual Meeting describing early outcomes and implementation metrics from commercial...

Neonatal DNA Methylation Signatures Associated With Subsequent Risk of Childhood Acute Lymphoblastic Leukemia

Investigators from Children’s Hospital Los Angeles (CHLA) have reported evidence that epigenetic differences measurable at birth are associated with later development of childhood acute...

Natera Acquires Foresight Diagnostics

Natera, has announced the completion of its acquisition of Foresight Diagnostics, a molecular oncology diagnostics company specializing in ultrasensitive detection of circulating tumor DNA...

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